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Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlifein recent years there has been increasing concern regarding potential adverse human health effects of various environmental contaminants designated by some scientists as endocrine disruptors thomas and colborn 1992 colborn et al 1993 and referred to in this report as hormonally active agents haas these concerns have originated in part from observations of developmental and hormonally active agents in the environment 1999 board on environmental studies and toxicology topics natural resources and ecology environmental quality health and management environmental health ecological studies environmental impact hormonally active agents in the environment by committee on harmonally active agents in the environment national res national research council u s hardcover available at half price books httpswwwhpbcomalthough there is evidence of harmful health and ecological effects associated with exposure to high doses of chemicals known as hormonally active agents or endocrine disrupters little is understood about the harm posed by exposure to the substances at low concentrations such as those that typically exist in the environment says a new report from a national research council committee

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